hemorrhagic disease of the newborn oral vitamin k

Prevention of hemorrhagic disease in the newborn. Late hemorrhagic disease of the newborn (HDN) presents 0.5–6 months after birth with mucocutaneous and intracranial bleeding. Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Vitamin K deficiency ) that could possibly cause Vitamin K deficiency includes:Newborn ( type of Immune deficiency conditions) - many neonates have vitamin K deficiency at birthVitamin K malabsorptionMalabsorption Breastfed newborns have been found to be particularly vulnerable to VKDB. Vitamin K deficiency bleeding (VKDB) is a bleeding problem that occurs in some newborns during the first few days of life. Vitamin K administration is for the prevention of hemorrhagic disease of the newborn. Early HDN is seen within 24 hours of birth in infants whose mothers have been on anticonvulsant or anti-tuberculous drugs during pregnancy. Vitamin K may be used in cases of ongoing IV feeding. The updated statement from 2003 makes a similar statement: “Prevention of early vitamin K deficiency bleeding (VKDB) of the newborn, with onset at birth to 2 weeks of age (formerly known as classic hemorrhagic disease of the newborn), by oral or parenteral administration of vitamin K is accepted practice.” Vitamin K deficiency may cause unexpected bleeding (0.25% to 1.7% incidence) during the first week of life in previously healthy-appearing neonates (classic hemorrhagic disease of the newborn [HDN]). Vitamin K plays an important role in blood clotting. Our Specials. Unless other evidence supporting an association between vitamin K and cancer appears, there is no reason to abandon the routine administration of vitamin K … Phytomenadione (fat soluble formulation) is used to antagonise the effects of vitamin K antagonist oral anticoagulants, e.g. after birth to all neonates. Aim of Study: This is a comparative study to evaluate the efficacy of oral Vitamin K and parenteral Vitamin K. Materials and Methods: 150 breastfed infants weighing more than 2.5 kg were evaluated to find out the efficacy of different routes of administration of Vitamin K to prevent hemorrhagic disease of newborn. Bleeding is usually intracranial, subgaleal, gastrointestinal, or nasal. Menu. It’s also used to prevent severe bleeding (hemorrhagic disease) in newborns. Pediatrics and Communicable Diseases Vitamin K Shots for Newborns: Questions and Answers - 6 - • The regimens used in Europe all involve multiple oral doses of vitamin K – an initial dose at birth, and subsequent doses daily, weekly, or monthly doses for many months. Vitamin K does not move easily across the placenta from the mother to the baby. Oral route is a better alternative. Vitamin K deficiency bleeding is a problem that occurs in some newborns. This prevents Hemorrhagic Disease of the Newborn (HDN). oral prophylactic regimens of vitamin K in Australia, Britain, Canada, Germany, New Zealand and Switzerland has shed new light on the incidence and epidemiology of hemorrhagic disease of the newborn (HDNB) in these countries. Vitamin K and the Clotting Cascade Vitamin K is a key cofactor for some of the most important factors in the coagulation cascade. Oral doses of 2mg are adequate. Vitamin K Deficiency Bleeding (aka “Hemorrhagic Disease of the Newborn”) can result; Incidence of VKDB reported varies from 1.5% to 0.001% , depending on population studied and feeding patterns (formula is protective since it’s supplemented with vit K) Disease •2. Use of oral vitamin K1 to prevent hemorrhagic disease of the newborn infant. Two series reported bleeding (some very serious) in the babies of 14 of 21 mothers and 8 of 111 mothers. VKDB is categorized as early-onset (within 24 hours after birth ), classic (within 4 weeks ), or late-onset (between 2–8 months). Babies often have a low level of vitamin K for a variety of reasons. In contrast, late VKDB, with onset from 2 to 12 weeks of age, is most effectively prevented by parenteral administration of … Certain internal and external factors place newborn infants at higher risk for VKDB. The newborn infant is usually given vitamin K after birth to prevent a life-threatening disease called hemorrhagic disease of the newborn. Corpus ID: 32303834. It must be given by injection, since oral vitamin K has not been shown to be as effective, and thereare no oral vitamin K preparations available for pediatric use in … It can be prevented with the administration of vitamin K in the first hours of life. Policies for giving babies vitamin K prophylactically at birth have been dictated, over the last 60 years, more by what manufacturers decided on commercial grounds to put on the market, than by any informed understanding of what babies actually need, or how it can most easily be given. Vitamin K is needed to form blood clots and to stop bleeding. For early and classic forms of hemorrhagic disease of the newborn, oral vitamin K (2mg dose) repeated at 2-4 weeks and at 6-8 weeks. Intramuscular administration of vitamin K for prophylaxis against hemorrhagic disease of the newborn has the disadvantage of increased cost, pain, anxiety to parents and risk of transmission of infection. Download as PDF. Overview. Data were obtained from the annual reports and Prevention of early vitamin K deficiency bleeding (VKDB) of the newborn, with onset at birth to 2 weeks of age (formerly known as classic hemorrhagic disease of the newborn), by oral or parenteral adminis-tration of vitamin K is accepted practice. Policies for giving babies vitamin K prophylactically at birth have been dictated, over the last 60 years, more by what manufacturers decided on commercial grounds to put on the market, than by any informed understanding of what babies actually need, or how it can most easily be given. italian passport renewal appointment. It happens during the first few days of life. We describe here two cases of late HDN in infants who received vitamin K. The first case is a previously healthy breastfed male who received one dose of oral vitamin K at birth and developed an intracranial hemorrhage 5 weeks later. The pharmacology and use of these drugs is discussed in separate topic reviews. Vitamin K ... •Controversy re oral versus parenteral use of routine Vit K largely resolved ... Vitamin K and Hemorrhagic Disease of the Newborn Late hemorrhagic disease of the newborn (HDN) presents 0.5-6 months after birth with mucocutaneous and intracranial bleeding. Late hemorrhagic disease of the newborn (HDN) presents 0.5–6 months after birth with mucocutaneous and intracranial bleeding. warfarin. Case presentation We present the case of a 2 months and 20 days Caucasian male, presented for bleeding from the injections … Traditionally, we give a Vitamin K shot at birth to prevent hemorrhagic disease of the newborn. Coagulation factors II,VII, IX, X and other Gla-proteins ( protein C, protein S, protein Z) also depend on the presence of … disease of the newborn (HDN). Comparison of oral and parenteral vitamin K prophylaxis for prevention of late hemorrhagic disease of the newborn J Pediatr . The efficacy of neonatal vitamin K prophylaxis (either oral or parenteral) in the prevention of classic HDN is firmly established. A deficiency in vitamin K is the main cause of hemorrhagic disease in newborn babies. Hemorrhagic disease of the newborn is a life-threatening condition associated with high mortality and morbidity. In 1999, the term hemorrhagic disease of the newborn was changed to vitamin K deficiency bleeding to reflect that this problem can occur later in infancy (Sutor et al., 1999). Vitamin K deficiency is rare except in neonates and patients with predisposing conditions including hepatobiliary or pancreatic disease. Introduction Any haemorraghic manifestation due to deficiency of vitamin K dependent clotting factors is known as Haemorraghic disease of newborn (HDN). Treatment of Hemorrhagic Disease of the Newborn. Severe vitamin K deficiency can develop quickly in breast fed infants and can result in the appearance of classic VKDB during the first week of life or late VKDB during the first two months of life. Vitamin K deficiency can lead to excessive and severe bleeding. Hot Deals. Prevention of early vitamin K deficiency bleeding (VKDB) of the newborn, with onset at birth to 2 weeks of age (formerly known as classic hemorrhagic disease of the newborn), by oral or parenteral administration of vitamin K is accepted practice. For most people, the primary dietary source of vitamin K is green leafy vegetables. For early and classic forms of hemorrhagic disease of the newborn, the treatment is with oral vitamin K (2mg dose) repeated at 2-4 weeks and at 6-8 weeks. Context In an infant, vitamin K deficiency can cause bleeding known as HDN or vitamin K deficiency bleeding (VKDB). All newborn infants should receive vitamin K prophylaxis. 2. With the current increase of delayed hemorrhagic disease as a result of breast-feeding and other nutritional changes, we may also be able to identify at-risk infants for whom the routine administration of an oral preparation of vitamin K at timely intervals during the first year of life may eliminate or decrease this potentially fatal disorder. Hemorrhagic disease in newborn: prophylaxis: single IM dose 0.5-1mg within 1 hour of birth, may repeat in 2-3 weeks. Late hemorrhagic disease of the newborn (HDN) presents 0.5–6 months after birth with mucocutaneous and intracranial bleeding. It can present through three distinct forms: early, classical and late. 1: Classical: Usually bleeding between day 2 and 5. Sometimes this bleeding is visible to parents and care providers, for example if the baby is bleeding without stopping from the cord site or a scratch on her face. It can also occur if mother is on anti-tuberculous therapy (rifampicin and isoniazid). }, author={Henrik Dam and H Dyggve and H Larsen and Preben Plum}, journal={Advances in pediatrics}, year={1952}, volume={5}, pages={ 129-53 } } It is ineffective against the newer oral anticoagulants. ... hemorrhagic disease of newborn download. OBJECTIVE: To determine (1) the most effective method of administering vitamin K to infants to prevent hemorrhagic disease of the newborn (HDNB) and (2) the safest method, in light of preliminary evidence suggesting that intramuscular administration of vitamin K is associated with childhood cancer. For the late form of the disease, oral vitamin K is not as efficacious as parenteral, and hence currently, 0.5-1 mg single IM dose is administered to infants. Hemorrhagic disease of the newborn PDF. • Intramuscular (IM) Therapy: VKDB is caused by vitamin K deficiency. Our Specials. Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Consultations. The baseline incidence of late vitamin K dependent bleeding (VKDB) is 4.4-8.6 per 100,000 infants. 1 mg IM, 1-2 mg orally after first feeding Is oral Vitamin K recommended for infants? Newborn infants have low stores of vitamin K, and human … Why is vitamin K important? He … Newborns are inherently vitamin K deficient at birth due to lower stores as well as a decreased ability to utilize vitamin K. In newborns, HDNB is typically caused by vitamin K deficiency due to insufficient prenatal storage of vitamin K, combined with insufficient vitamin K in breast milk. Term newborns have a vitamin K … Vitamin K deficiency bleeding (VKDB), formerly known as hemorrhagic disease of the newborn (HDN), is a bleeding disorder in neonates that is caused by inadequate serum levels of vitamin K. Vitamin K is a nutrient essential for adequate function of the coagulation cascade. Vitamin K and Hemorrhagic Disease of the Newborn Presented by :-Kamlah olaimat 27\7\2010. Healthy newborn infants should receive vitamin K either: by intramuscular injection of 1 mg (0.1 mL) at birth, or; as three 2 mg (0.2 mL) oral doses given at birth, at the time of newborn screening between three to five days of age and again in the fourth week. NICE guidelines (1) recommend that all newborn babies should be given a dose of Vitamin K to prevent HDN. Although oral vitamin K is available, there is no version for newborns approved by the U.S. Food and Drug Administration (FDA), and if a … • The baseline incidence of VKDB is 4.4-8.6 per 100,000 infants. Intramuscular Therapy: A single-dose of intramuscular vitamin K reduces this risk to approximately 1 per 1,000,000 infants (81 fold). oral vitamin k for newborns aap Your Cart. This condition is called Vitamin K Deficiency Bleeding (VKDB). HDN is a bleeding disorder. A condition characterized as a coagulation disturbance in newborns due to vitamin K deficiency resulting in impaired production of coagulation factors II, VII, IX, and X, and proteins C and S by the liver. … Babies are normally born with low levels of vitamin K, an essential factor in blood clotting. In some cases, this leads to serious bleeding from the stomach, umbilicus (navel) or intestine (gut) and in a few cases to bleeding in the brain. Newborn Vitamin K Newborns & Vitamin K ... – formerly called Hemorrhagic Disease of the Newborn. A lack of vitamin K may cause severe bleeding in newborn babies. It is also used to prevent vitamin K deficiency bleeding in neonates (hemorrhagic disease of the newborn). Vitamin K deficiency bleeding (VKDB) of the newborn, previously known as haemorrhagic disease of the newborn, is a rare form of bleeding disorder that affects newborns and young infants due to low stores of vitamin K at birth. Vitamin K deficiency is one of the most common causes of bleeding in healthy infants. We describe here two cases of late HDN in infants who received vitamin K. treatment: 1mg SQ or IM, in conjunction with proper laboratory testing of PT. Hemorrhagic disease is a bleeding problem that occurs in a baby during the first few days of life. Background Vitamin K, a fat soluble vitamin, is a necessary cofactor for the activation of coagulation factors II, VII, IX, X, and protein C and S. In neonatal period, vitamin K deficiency may lead to Vitamin K Deficiency Bleeding (VKDB). The relation of vitamin K deficiency to hemorrhagic disease of the newborn. Refusal of Vitamin K in Newborn Revised 8/2014 Refusal of Vitamin K in Newborn The American Academy of Pediatrics (AAP) recommends every newborn receive a shot of vitamin K within one hour of birth. HDN is a rare but serious, and sometimes fatal, bleeding disorder. How much vitamin K is needed to prevent hemorrhagic disease of the newborn? Without vitamin K, blood cannot clot normally and the baby can develop a tendency to bleed easily. A single intramuscular dose of Vitamin K 1 Injection 0.5 to 1 mg within one hour of birth is recommended. Hot Deals. Vitamin K occurs in two forms, vitamin K1 whose source is dietary intake and This is preferred since not all bleeding in the newborn is due to vitamin K deficiency and bleeding due to this cause is not confined to the newborn. Each patient should be examined individually to determine the needed dosage and route, but each newborn should always receive vitamin K supplements in some form. Vitamin K is required for the synthesis of coagulation factors, being essential for blood clotting. As infant formulas contain vitamin K, it is unlikely that fully formula-fed infants require the third oral dose. The term ‘vitamin K deficiency bleeding’ (VKDB) has now been adopted (Sutor et al 1999). Oral Vitamin K seems to work well for the early and classic, but not the Late onset. Vitamin K injection can prevent hemorrhagic disease of the newborn. Home; Cruise Deals. Key words: Intracranial bleed, Late hemorrhagic disease of newborn, Vitamin K. Hemorrhagic disease of the newborn (HDN) has three distinct patterns of presentation(1-3). Abstract. Vitamin K is used to prevent and treat certain blood clotting (coagulation) issues. Both bile acid malabsorption and cholestyramine can be associated with vitamin K deficiency. 1986 Apr;108(4):616-9. doi: 10.1016/s0022-3476(86)80851-4. Internet bloggers have made pediatricians unwitting victims of their success with the standard use of intramuscular vitamin K prophylaxis in every newborn since 1961, and they are gambling with some infants’ brains and lives in a dangerous game of intracranial roulette. Jump to section: Unless other evidence supporting an association between vitamin K and cancer appears, there is no reason to abandon the routine administration of vitamin K … The chief etiology is vitamin K (vitamin K) deficiency. long-term prophylaxis of haemorrhagic disease of the newborn Near term or term infants with an intravenous line in situ should be administered Vitamin K IM due to the increased clearance of Vitamin K when given intravenously Related clinical guidelines Vitamin K Administration- Neonate References Society of Hospital Pharmacists of Australia. Oral administration of a single dose of vitamin K soon after is associated with significant biochemical vitamin K deficiency by 1 month of age, but the relation of biochemical abnormality to clinical manifestations of late hemorrhagic disease of the newborn is less clear. We describe here two cases of late HDN in infants who received vitamin K. The first case is a previously healthy breastfed male who received one dose of oral vitamin K at birth and developed an intracranial hemorrhage 5 weeks … The benefit of neonatal vitamin K prophylaxis against hemorrhagic disease of the newborn have been well described. Hemorrhagic disease of the newborn (HDNB) was first identified over 100 years ago by Townsend ; it presents as unexpected bleeding, often with gastrointestinal hemorrhage and ecchymosis, and, in many cases, intracranial hemorrhage.In 1961, the Committee on Nutrition of the American Academy of Pediatrics (AAP) recommended that vitamin K 1 (hereafter … As a result, a newborn does not have much vitamin K stored up at birth. association between oral vitamin K and childhood cancer reported by Golding et al was based on one dose of vitamin K at birth, repeated doses, or a variety of different regimens among the cases and controls. oral prophylactic regimens of vitamin K in Australia, Britain, Canada, Germany, New Zealand and Switzerland has shed new light on the incidence and epidemiology of hemorrhagic disease of the newborn (HDNB) in these countries. after birth to all neonates. VKDB was previously called hemorrhagic disease of the newborn. Hemorrhagic disease of the newborn, also referred to as vitamin K deficiency bleeding (VKDB), is a totally … Vitamin K is necessary for normal blood clotting in adults and children. Some babies (in fact, most of them) are born with insufficient vitamin K levels. In some newborns, this deficiency can lead to a serious bleeding disorder, typically in the first week of life, called Hemorrhagic Disease of the Newborn (HDN). long-term prophylaxis of haemorrhagic disease of the newborn Near term or term infants with an intravenous line in situ should be administered Vitamin K IM due to the increased clearance of Vitamin K when given intravenously Related clinical guidelines Vitamin K Administration- Neonate References Society of Hospital Pharmacists of Australia. By a pure fluke a 1 mg IM dose, designed to prevent early vitamin deficiency … Oral administration of a single dose of vitamin K soon after is associated with significant biochemical vitamin K deficiency by 1 month of age, but the relation of biochemical abnormality to clinical manifestations of late hemorrhagic disease of the newborn is less clear. Vitamin K deficiency bleeding is a problem that occurs in some newborns. Per Unit; Description . Newborns who present at a greater risk for hemorrhage disease of newborns may need an injection rather than an oral supplement to ensure that the disease is controlled. Vitamin K is a fat soluble vitamin, absorbed in the terminal ileum, and is dependent on functioning villi, bile acid, and fat absorption. It happens during the first few days of life. But, it can easily be prevented by administering 1 mg IM of vitamin K within 1 hour of birth. In an infant, vitamin K deficiency can cause bleeding known as HDN or vitamin K deficiency bleeding (VKDB). Home; Cruise Deals. Vitamin K deficiency at birth is a risk factor for the Hemorrhagic disease of the newborn or Vitamin K deficiency bleeding (VKDB). Women in this situation should be treated with oral vitamin K 20mg/day for 2 weeks prior to delivery. Data were obtained from the annual reports and The American Academy of Pediatrics recommends that vitamin K 1 be given to the newborn. Vitamin K and the Clotting Cascade Vitamin K is a key cofactor for some of the most important factors in the coagulation cascade. Babies are born with very small amounts of vitamin K stored in their bodies, which can lead to serious bleeding problems like vitamin K deficiency bleeding (VKDB). This pro-hemorrhagic condition can produce severe bleeding mainly in the skin, the gastrointestinal tract, and the brain. Vitamin K deficiency bleeding or VKDB, occurs when babies cannot stop bleeding because their blood does not have enough Vitamin K to form a clot. VKDB is rare in industrialized countries because most children receive a. vitamin K. injection at birth. Vitamin K deficiency bleeding (VKDB) is a bleeding problem that occurs in some newborns during the first few days of life. VKDB was previously called hemorrhagic disease of the newborn. What causes vitamin K deficiency bleeding? Babies are normally born with low levels of vitamin K, an essential factor in blood clotting. Oral absorption of vitamin K has been shown to be equally good using special oral preparations. Children may be especially sensitive to the effects and side effects of vitamin K. Neonates, especially premature neonates, may be more sensitive than older children. For the late form of … @article{Dam1952TheRO, title={The relation of vitamin K deficiency to hemorrhagic disease of the newborn. italian passport renewal appointment. In. Vitamin K antagonists (VKA) are a class of drugs used for therapeutic anticoagulation. Topics •1. Both forms of the disease can be severe, causing brain damage and death. Hemorrhagic Disease of Newborn (HDN) is a common cause of bleeding in infancy. : Monitor for side effects and adverse reactions. Early and prompt diagnosis of hemorrhagic disease of the newborn can alleviate the devastating consequences. Vitamin K shots are given to infants to prevent Hemorrhagic Disease of the Newborn (HDN) Giving newborns a syringe full of vitamin K may cause psychological trauma, give infants 20,000 times more vitamin K dose than what is needed, and create an environment for infections to occur. The updated statement from 2003 makes a similar statement: “Prevention of early vitamin K deficiency bleeding (VKDB) of the newborn, with onset at birth to 2 weeks of age (formerly known as classic hemorrhagic disease of the newborn), by oral or parenteral administration of vitamin K is accepted practice.” (CDC. Vitamin K helps the blood to clot but the body's capacity to store it is very low. Vitamin K Deficiency Bleeding is also known as haemorrhagic disease of the newborn (HDN) and vitamin K deficient bleeding in the newborn. Waddell et al showed that vitamin K prevents hemorrhagic disease of the newborn. This condition used to be called hemorrhagic disease of the newborn. Haemorrhagic Disease of Newborn Dr.Rabi Dhakal 2. Hemorrhagic disease of the newborn •A moderate decrease in factors II,VII,IX,X normally occurs in all newborn infants by 48-72 hours after birth, this is probably due to lack of free Vit K from the mother and absence of bacterial intestinal flora normally responsible for Vit K synthesis •Rarely in term and more frequently in preter … The early disease occurs within the first 24 h of life and cannot be prevented by prophylactic administration of vitamin K to the newborn. The bleeding can occur anywhere on the inside or outside of the body. It commonly presents with intracranial haemorrhage with the risk of brain damage or death.. The pharmacology and use of these drugs is discussed in separate topic reviews. Vitamin K antagonists (VKA) are a class of drugs used for therapeutic anticoagulation. The benefit of neonatal vitamin K prophylaxis against hemorrhagic disease of the newborn have been well described. There are three types of presentations of HDN according to the time of onset-early, classical and late. Vitamin K deficiency bleeding (VKDB) occurs when a baby experiences severe intestinal or other, including intracranial bleeding, which can result in permanent brain damage or death. Vitamin K deficiency is rare except in neonates and patients with predisposing conditions including hepatobiliary or pancreatic disease. Menu. brick and brew malvern menu. Prophylactic vitamin K for vitamin K deficiency bleeding in neonates. administration of oral Vitamin K. Background and Summary of the Evidence • Vitamin K administration is for the prevention of hemorrhagic disease of the newborn, also known as vitamin K dependent bleeding (VKDB). Haemorrhagic disease of the newborn (HDN). From: Case Studies in Public Health, 2018. In 1999, the term hemorrhagic disease of the newborn was changed to vitamin K deficiency bleeding to reflect that this problem can occur later in infancy (Sutor et al., 1999). Vitamin K was first synthesized in 1939 and in 1961 the committee on nutrition of the American Academy of Pediatrics first recommended postnatal prophylaxis for classic VKDB using 0.5 to 1.0 mg vitamin K parenterally or 1.0 to 2.0 mg orally . Vitamin K deficiency bleeding usually warrants consultation with a pediatric hematologist to rule out other causes of hemorrhagic disease of the newborn. By a pure fluke a 1 mg IM dose, designed to prevent early vitamin deficiency … Mother may receive 1-5mg 12-24 hours before delivery. 1991 Sep;119(3):461-4. doi: 10.1016/s0022-3476(05)82064-5. VKDB can lead to brain damage and death. Causes of hemorrhagic disease of the newborn. Newborn Hemorrhagic Disease. It may also be used when antibiotics have killed bacteria in the intestines that make vitamin K. Carnival Special Offers; Celebrity Special Offers Use of oral vitamin K1 to prevent hemorrhagic disease of the newborn infant J Pediatr. HDN can occur up to six months of age, and can almost always be prevented by giving extra Vitamin K. What are the benefits of giving Vitamin K? Vitamin K is important in the clotting cascade, and vitamin K prophylaxis is important in preventing vitamin K deficiency bleeding (VKDB) in newborns. Haemorrhagic disease of newborn 1. oral vitamin k for newborns aap 3. Three types of vitamin K deficiency bleeding (VKDB) have been classified: early onset (occurring in the first 24 hours post-birth), classic (occurring at days 2 to 7) and late onset (at 2 to 12 weeks and up to 6 … An international comparison of intramuscular (IM) versus oral prophylactic regimens of vitamin K in Australia, Britain, Canada, Germany, New Zealand and Switzerland has shed new light on the incidence and epidemiology of hemorrhagic disease of the newborn (HDNB) in these countries. Some patients will still be at risk – those who have absorption problems like: Cholestyramine is a bile acid sequestrant used in the management of bile acid malabsorption. Routine newborn care includes the prophylactic administration of Vitamin K to the baby at birth to prevent the occurrence of Hemorrhagic Disease of the Newborn (HDN). Newborn levels are considerably lower than maternal levels. We describe here two cases of late HDN in infants who received vitamin K. Vitamin K is given within an hour of birth to prevent hemorrhagic disease of the newborn, a potentially fatal condition. Abstract. Carnival Special Offers; Celebrity Special Offers This condition used to be called hemorrhagic disease of the newborn.

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